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Molecular Simulations Illuminate the Role of Regulatory Components of the RNA Polymerase from the Hepatitis C Virus in Influencing Protein Structure and Dynamics
[Image: see text] The RNA polymerase (gene product NS5B) from the hepatitis C virus is responsible for replication of the viral genome and is a validated drug target for new therapeutic agents. NS5B has a structure resembling an open right hand (containing the fingers, palm, and thumb subdomains), a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3961064/ https://ncbi.nlm.nih.gov/pubmed/23738897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi400251g |
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