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Using the Hepatitis C Virus RNA-Dependent RNA Polymerase as a Model to Understand Viral Polymerase Structure, Function and Dynamics

Viral polymerases replicate and transcribe the genomes of several viruses of global health concern such as Hepatitis C virus (HCV), human immunodeficiency virus (HIV) and Ebola virus. For this reason they are key targets for therapies to treat viral infections. Although there is little sequence simi...

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Dades bibliogràfiques
Publicat a:Viruses
Autors principals: Sesmero, Ester, Thorpe, Ian F.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4517137/
https://ncbi.nlm.nih.gov/pubmed/26193306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7072808
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