RAD21 cohesin overexpression is a prognostic and predictive marker exacerbating poor prognosis in KRAS mutant colorectal carcinomas

BACKGROUND: RAD21 is a component of the cohesion complex and is integral to chromosome segregation and error-free DNA repair. RAD21 is functionally important in tumour progression but its role in colorectal carcinoma (CRC) is unclear. We therefore assessed its clinicopathological and prognostic sign...

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Autores principales: Deb, S, Xu, H, Tuynman, J, George, J, Yan, Y, Li, J, Ward, R L, Mortensen, N, Hawkins, N J, McKay, M J, Ramsay, R G, Fox, S B
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960611/
https://ncbi.nlm.nih.gov/pubmed/24548858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2014.31
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