Rad21-Cohesin Haploinsufficiency Impedes DNA Repair and Enhances Gastrointestinal Radiosensitivity in Mice

Approximately half of cancer-affected patients receive radiotherapy (RT). The doses delivered have been determined upon empirical experience based upon average radiation responses. Ideally higher curative radiation doses might be employed in patients with genuinely normal radiation responses and imp...

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Detalhes bibliográficos
Main Authors: Xu, Huiling, Balakrishnan, Kuhendra, Malaterre, Jordane, Beasley, Matthew, Yan, Yuqian, Essers, Jeroen, Appeldoorn, Esther, Thomaszewski, Jonathan M., Vazquez, Melisa, Verschoor, Sandra, Lavin, Martin F., Bertonchello, Ivan, Ramsay, Robert G., McKay, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920816/
https://ncbi.nlm.nih.gov/pubmed/20711430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012112
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