Rad21-Cohesin Haploinsufficiency Impedes DNA Repair and Enhances Gastrointestinal Radiosensitivity in Mice

Approximately half of cancer-affected patients receive radiotherapy (RT). The doses delivered have been determined upon empirical experience based upon average radiation responses. Ideally higher curative radiation doses might be employed in patients with genuinely normal radiation responses and imp...

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Autori principali: Xu, Huiling, Balakrishnan, Kuhendra, Malaterre, Jordane, Beasley, Matthew, Yan, Yuqian, Essers, Jeroen, Appeldoorn, Esther, Thomaszewski, Jonathan M., Vazquez, Melisa, Verschoor, Sandra, Lavin, Martin F., Bertonchello, Ivan, Ramsay, Robert G., McKay, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920816/
https://ncbi.nlm.nih.gov/pubmed/20711430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012112
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