Cell biological steps and checkpoints in accessing NK cell cytotoxicity

Natural killer (NK) cell-mediated cytotoxicity is governed by the formation of a lytic immune synapse in discrete regulated steps, which give rise to an extensive array of cellular checkpoints in accessing NK cell-mediated cytolytic defense. Appropriate progression through these cell biological step...

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Detalhes bibliográficos
Main Authors: Mace, Emily M, Dongre, Prachi, Hsu, Hsiang-Ting, Sinha, Papiya, James, Ashley M, Mann, Shaina S, Forbes, Lisa R, Watkin, Levi B, Orange, Jordan S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3960583/
https://ncbi.nlm.nih.gov/pubmed/24445602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2013.96
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