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Stereoselective terminal functionalization of small peptides for catalytic asymmetric synthesis of unnatural peptides
The asymmetric phase-transfer catalytic alkylation of peptides has been achieved by the use of designed C(2)-symmetric chiral quaternary ammonium bromide 1 as catalyst. Excellent stereoselectivities were uniformly observed in the alkylation with a variety of alkyl halides and the efficiency of the t...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC395993/ https://ncbi.nlm.nih.gov/pubmed/15079083 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307725101 |
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