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Stereoselective terminal functionalization of small peptides for catalytic asymmetric synthesis of unnatural peptides

The asymmetric phase-transfer catalytic alkylation of peptides has been achieved by the use of designed C(2)-symmetric chiral quaternary ammonium bromide 1 as catalyst. Excellent stereoselectivities were uniformly observed in the alkylation with a variety of alkyl halides and the efficiency of the t...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Maruoka, Keiji, Tayama, Eiji, Ooi, Takashi
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395993/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15079083/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307725101
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