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Cu(I)-catalyzed direct addition and asymmetric addition of terminal alkynes to imines

A Cu(I)-catalyzed direct addition of alkynes to imines was developed. The process is simple and provides a diverse range of propargylamines in high enantiomeric excess and good yield both in water and in toluene. The absolute configuration of such addition products has been determined by x-ray cryst...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Wei, Chunmei, Mague, Joel T., Li, Chao-Jun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2004
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC395979/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15067132/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307150101
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