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Cu(I)-catalyzed direct addition and asymmetric addition of terminal alkynes to imines

A Cu(I)-catalyzed direct addition of alkynes to imines was developed. The process is simple and provides a diverse range of propargylamines in high enantiomeric excess and good yield both in water and in toluene. The absolute configuration of such addition products has been determined by x-ray cryst...

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Detalhes bibliográficos
Main Authors: Wei, Chunmei, Mague, Joel T., Li, Chao-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395979/
https://ncbi.nlm.nih.gov/pubmed/15067132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307150101
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