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Copper-catalyzed asymmetric conjugate reduction as a route to novel β-azaheterocyclic acid derivatives

A chiral copper-hydride catalyst for the asymmetric conjugate reduction of α,β-unsaturated carbonyl compounds has been used for the reduction of substrates containing β-nitrogen substituents. A new set of reaction conditions has allowed for a variety of β-azaheterocyclic acid derivatives to be synth...

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Detalhes bibliográficos
Main Authors: Rainka, Matthew P., Aye, Yimon, Buchwald, Stephen L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395992/
https://ncbi.nlm.nih.gov/pubmed/15067136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307764101
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