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Involvement of heparanase in atherosclerosis and other vessel wall pathologies

Heparanase, the sole mammalian endoglycosidase degrading heparan sulfate, is causally involved in cancer metastasis, angiogenesis, inflammation and kidney dysfunction. Despite the wide occurrence and impact of heparan sulfate proteoglycans in vascular biology, the significance of heparanase in vesse...

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Autors principals: Vlodavsky, Israel, Blich, Miry, Li, Jin-Ping, Sanderson, Ralph D., Ilan, Neta
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3959806/
https://ncbi.nlm.nih.gov/pubmed/23499530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.matbio.2013.03.002
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