BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways

The fate of pluripotent stem cells is tightly controlled during early embryonic development. Both the derivation and the maintenance of embryonic stem cells (ES cells) in vitro depend on feeder cell-derived growth factors that are largely unidentified. To dissect the mechanisms governing pluripotenc...

Full description

Saved in:
Bibliographic Details
Main Authors: Qi, Xiaoxia, Li, Teng-Guo, Hao, Jing, Hu, Jie, Wang, Jing, Simmons, Holly, Miura, Shigeto, Mishina, Yuji, Zhao, Guang-Quan
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC395917/
https://ncbi.nlm.nih.gov/pubmed/15075392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401367101
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items