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BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways

The fate of pluripotent stem cells is tightly controlled during early embryonic development. Both the derivation and the maintenance of embryonic stem cells (ES cells) in vitro depend on feeder cell-derived growth factors that are largely unidentified. To dissect the mechanisms governing pluripotenc...

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Detalhes bibliográficos
Main Authors: Qi, Xiaoxia, Li, Teng-Guo, Hao, Jing, Hu, Jie, Wang, Jing, Simmons, Holly, Miura, Shigeto, Mishina, Yuji, Zhao, Guang-Quan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC395917/
https://ncbi.nlm.nih.gov/pubmed/15075392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0401367101
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