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Induction of primordial germ cells from murine epiblasts by synergistic action of BMP4 and BMP8B signaling pathways
Extraembryonic ectoderm-derived factors instruct the pluripotent epiblast cells to develop toward a restricted primordial germ cell (PGC) fate during murine gastrulation. Genes encoding Bmp4 of the Dpp class and Bmp8b of the 60A class are expressed in the extraembryonic ectoderm and targeted mutatio...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC35432/ https://ncbi.nlm.nih.gov/pubmed/11427739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.151242798 |
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