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Passive Immunization Against Marinobufagenin Attenuates Renal Fibrosis and Improves Renal Function in Experimental Renal Disease

BACKGROUND: We have shown that the cardiotonic steroid marinobufagenin (MBG) is elevated in clinical and experimental renal disease, and significantly contributes to the development of experimental uremic cardiomyopathy induced by removal of five-sixths of the kidney (5/6 nephrectomy; PNx) in the ra...

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Main Authors: Haller, Steven T., Drummond, Christopher A., Yan, Yanling, Liu, Jiang, Tian, Jiang, Malhotra, Deepak, Shapiro, Joseph I.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958603/
https://ncbi.nlm.nih.gov/pubmed/24014658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ajh/hpt169
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