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Monoclonal antibody against marinobufagenin reverses cardiac fibrosis in rats with chronic renal failure
BACKGROUND: Cardiotonic steroids (CTS) are implicated in pathophysiology of uremic cardiomyopathy. In the present study, we tested whether a monoclonal antibody (mAb) against the bufadienolide CTS, marinobufagenin (MBG), alleviates cardiac hypertrophy and fibrosis in partially nephrectomized (PNx) r...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3355226/ https://ncbi.nlm.nih.gov/pubmed/22378033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ajh.2012.17 |
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