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Cross Talk between CD3 and CD28 Is Spatially Modulated by Protein Lateral Mobility

Functional convergence of CD28 costimulation and TCR signaling is critical to T-cell activation and adaptive immunity. These receptors form complex microscale patterns within the immune synapse, although the impact of this spatial organization on cell signaling remains unclear. We investigate this c...

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Detalhes bibliográficos
Main Authors: Bashour, Keenan T., Tsai, Jones, Shen, Keyue, Lee, Joung-Hyun, Sun, Eileen, Milone, Michael C., Dustin, Michael L., Kam, Lance C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958039/
https://ncbi.nlm.nih.gov/pubmed/24379441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00842-13
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