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Micropatterning of costimulatory ligands enhances CD4(+) T cell function
Spatial organization of signaling complexes is a defining characteristic of the immunological synapse (IS), but its impact on cell communication is unclear. In T cell–APC pairs, more IL-2 is produced when CD28 clusters are segregated from central supramolecular activation cluster (cSMAC)-localized C...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2409411/ https://ncbi.nlm.nih.gov/pubmed/18505845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710295105 |
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