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Substrate rigidity regulates human T cell activation and proliferation()

Adoptive immunotherapy using cultured T cells holds promise for the treatment of cancer and infectious disease. Ligands immobilized on surfaces fabricated from hard materials such as polystyrene plastic are commonly employed for T cell culture. The mechanical properties of a culture surface can infl...

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Detalhes bibliográficos
Main Authors: O’Connor, Roddy S., Hao, Xueli, Shen, Keyue, Bashour, Keenan, Akimova, Tatiana, Hancock, Wayne W., Kam, Lance, Milone, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401283/
https://ncbi.nlm.nih.gov/pubmed/22732590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1102757
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