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Residual Complexes Containing SMARCA2 (BRM) Underlie the Oncogenic Drive of SMARCA4 (BRG1) Mutation

Collectively, genes encoding subunits of the SWI/SNF (BAF) chromatin remodeling complex are mutated in 20% of all human cancers, with the SMARCA4 (BRG1) subunit being one of the most frequently mutated. The SWI/SNF complex modulates chromatin remodeling through the activity of two mutually exclusive...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Wilson, Boris G., Helming, Katherine C., Wang, Xiaofeng, Kim, Youngha, Vazquez, Francisca, Jagani, Zainab, Hahn, William C., Roberts, Charles W. M.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2014
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958034/
https://ncbi.nlm.nih.gov/pubmed/24421395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01372-13
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