Virulence Factor NSs of Rift Valley Fever Virus Recruits the F-Box Protein FBXO3 To Degrade Subunit p62 of General Transcription Factor TFIIH

The nonstructural protein NSs is the main virulence factor of Rift Valley fever virus (RVFV; family Bunyaviridae, genus Phlebovirus), a serious pathogen of livestock and humans in Africa. RVFV NSs blocks transcriptional upregulation of antiviral type I interferons (IFN) and destroys the general tran...

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Detalhes bibliográficos
Main Authors: Kainulainen, Markus, Habjan, Matthias, Hubel, Philipp, Busch, Laura, Lau, Simone, Colinge, Jacques, Superti-Furga, Giulio, Pichlmair, Andreas, Weber, Friedemann
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957945/
https://ncbi.nlm.nih.gov/pubmed/24403578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02914-13
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