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Nuclear pore protein Nup98 is involved in replication of Rift Valley fever virus and nuclear import of virulence factor NSs

The non-structural protein NSs is the main virulence factor of Rift Valley fever virus, a major zoonotic pathogen in Africa. NSs forms large aggregates in the nucleus and impairs induction of the antiviral type I IFN system by several mechanisms, including degradation of subunit p62 of the general R...

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Bibliografiske detaljer
Udgivet i:J Gen Virol
Main Authors: Lau, Simone, Weber, Friedemann
Format: Artigo
Sprog:Inglês
Udgivet: Microbiology Society 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7660236/
https://ncbi.nlm.nih.gov/pubmed/31671053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/jgv.0.001347
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