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NSs amyloid formation is associated with the virulence of Rift Valley fever virus in mice

Amyloid fibrils result from the aggregation of host cell-encoded proteins, many giving rise to specific human illnesses such as Alzheimer’s disease. Here we show that the major virulence factor of Rift Valley fever virus, the protein NSs, forms filamentous structures in the brain of mice and affects...

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書誌詳細
出版年:Nat Commun
主要な著者: Léger, Psylvia, Nachman, Eliana, Richter, Karsten, Tamietti, Carole, Koch, Jana, Burk, Robin, Kummer, Susann, Xin, Qilin, Stanifer, Megan, Bouloy, Michèle, Boulant, Steeve, Kräusslich, Hans-Georg, Montagutelli, Xavier, Flamand, Marie, Nussbaum-Krammer, Carmen, Lozach, Pierre-Yves
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329897/
https://ncbi.nlm.nih.gov/pubmed/32612175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17101-y
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