NSs amyloid formation is associated with the virulence of Rift Valley fever virus in mice

Amyloid fibrils result from the aggregation of host cell-encoded proteins, many giving rise to specific human illnesses such as Alzheimer’s disease. Here we show that the major virulence factor of Rift Valley fever virus, the protein NSs, forms filamentous structures in the brain of mice and affects...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Léger, Psylvia, Nachman, Eliana, Richter, Karsten, Tamietti, Carole, Koch, Jana, Burk, Robin, Kummer, Susann, Xin, Qilin, Stanifer, Megan, Bouloy, Michèle, Boulant, Steeve, Kräusslich, Hans-Georg, Montagutelli, Xavier, Flamand, Marie, Nussbaum-Krammer, Carmen, Lozach, Pierre-Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7329897/
https://ncbi.nlm.nih.gov/pubmed/32612175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-17101-y
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