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A Novel Poxvirus-Based Vaccine, MVA-CHIKV, Is Highly Immunogenic and Protects Mice against Chikungunya Infection

There is a need to develop a single and highly effective vaccine against the emerging chikungunya virus (CHIKV), which causes a severe disease in humans. Here, we have generated and characterized the immunogenicity profile and the efficacy of a novel CHIKV vaccine candidate based on the highly atten...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: García-Arriaza, Juan, Cepeda, Victoria, Hallengärd, David, Sorzano, Carlos Óscar S., Kümmerer, Beate Mareike, Liljeström, Peter, Esteban, Mariano
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3957920/
https://ncbi.nlm.nih.gov/pubmed/24403588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.03418-13
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