Distinct Immunogenicity and Efficacy of Poxvirus-Based Vaccine Candidates against Ebola Virus Expressing GP and VP40 Proteins

Zaire and Sudan ebolavirus species cause a severe disease in humans and nonhuman primates (NHPs) characterized by a high mortality rate. There are no licensed therapies or vaccines against Ebola virus disease (EVD), and the recent 2013 to 2016 outbreak in West Africa highlighted the need for EVD-spe...

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Bibliographic Details
Published in:J Virol
Main Authors: Lázaro-Frías, Adrián, Gómez-Medina, Sergio, Sánchez-Sampedro, Lucas, Ljungberg, Karl, Ustav, Mart, Liljeström, Peter, Muñoz-Fontela, César, Esteban, Mariano, García-Arriaza, Juan
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5952144/
https://ncbi.nlm.nih.gov/pubmed/29514907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00363-18
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