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Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels
We identified a mutation in the Diet1 gene in a mouse strain that is resistant to hyperlipidemia and atherosclerosis. Diet1 encodes a 236 kD protein consisting of tandem low density lipoprotein receptor and MAM (meprin-A5-protein tyrosine phosphatase mu) domains, and is expressed in enterocytes of t...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2013
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3956443/ https://ncbi.nlm.nih.gov/pubmed/23747249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cmet.2013.04.007 |
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