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Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants
Diet1 modulates intestinal production of the hormone, fibroblast growth factor (FGF)15, which signals in liver to regulate bile acid synthesis. C57BL/6ByJ mice with a spontaneous Diet1-null mutation are resistant to hypercholesterolemia compared with wild-type C57BL/6J mice through enhanced choleste...
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Publicado no: | J Lipid Res |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
The American Society for Biochemistry and Molecular Biology
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5832924/ https://ncbi.nlm.nih.gov/pubmed/29295820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M078279 |
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