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The human immunodeficiency virus type 1 Vpr protein upregulates PVR via activation of the ATR-mediated DNA damage response pathway

Viral infection may induce the cell-surface expression of PVR (CD155) that, upon recognition by its cognate activating DNAM-1 receptor present on cytotoxic lymphocytes, may promote antiviral immune responses. Here we show that expression of the human immunodeficiency virus type 1 (HIV-1) Vpr protein...

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Detalhes bibliográficos
Main Authors: Vassena, Lia, Giuliani, Erica, Matusali, Giulia, Cohen, Éric A., Doria, Margherita
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955189/
https://ncbi.nlm.nih.gov/pubmed/24045107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.055541-0
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