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The HIV-1 Tat protein modulates CD4 expression in human T cells through the induction of miR-222

Several cellular microRNAs show substantial changes in expression during HIV-1 infection and their active role in the viral life cycle is progressively emerging. In the present study, we found that HIV-1 infection of Jurkat T cells significantly induces the expression of miR-222. We show that this i...

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Detalhes bibliográficos
Main Authors: Orecchini, Elisa, Doria, Margherita, Michienzi, Alessandro, Giuliani, Erica, Vassena, Lia, Ciafrè, Silvia Anna, Farace, Maria Giulia, Galardi, Silvia
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4075518/
https://ncbi.nlm.nih.gov/pubmed/24717285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.28372
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