Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation

MicroRNAs (miRNAs) are potent post-transcriptional regulators of protein coding genes. Patterns of misexpression of miRNAs in cancer suggest key functions of miRNAs in tumorigenesis. However, current bioinformatics tools do not entirely support the identification and characterization of the mode of...

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Detalhes bibliográficos
Main Authors: le Sage, Carlos, Nagel, Remco, Egan, David A, Schrier, Mariette, Mesman, Elly, Mangiola, Annunziato, Anile, Corrado, Maira, Giulio, Mercatelli, Neri, Ciafrè, Silvia Anna, Farace, Maria Giulia, Agami, Reuven
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949005/
https://ncbi.nlm.nih.gov/pubmed/17627278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601790
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