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Regulation of the p27(Kip1) tumor suppressor by miR-221 and miR-222 promotes cancer cell proliferation

MicroRNAs (miRNAs) are potent post-transcriptional regulators of protein coding genes. Patterns of misexpression of miRNAs in cancer suggest key functions of miRNAs in tumorigenesis. However, current bioinformatics tools do not entirely support the identification and characterization of the mode of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: le Sage, Carlos, Nagel, Remco, Egan, David A, Schrier, Mariette, Mesman, Elly, Mangiola, Annunziato, Anile, Corrado, Maira, Giulio, Mercatelli, Neri, Ciafrè, Silvia Anna, Farace, Maria Giulia, Agami, Reuven
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1949005/
https://ncbi.nlm.nih.gov/pubmed/17627278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601790
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