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The Human Immunodeficiency Virus Type 1 Nef and Vpu Proteins Downregulate the Natural Killer Cell-Activating Ligand PVR

The human immunodeficiency virus type 1 (HIV-1) evades the immune responses of natural killer (NK) cells through mechanisms that have been partially deciphered. Here we show that in HIV-1-infected T lymphocytes, the early viral Nef protein downmodulates PVR (CD155, Necl-5), a ligand for the activati...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Matusali, Giulia, Potestà, Marina, Santoni, Angela, Cerboni, Cristina, Doria, Margherita
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3318642/
https://ncbi.nlm.nih.gov/pubmed/22301152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05788-11
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