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HIV-1 Nef and Vpu Interfere with L-Selectin (CD62L) Cell Surface Expression To Inhibit Adhesion and Signaling in Infected CD4(+) T Lymphocytes

Leukocyte recirculation between blood and lymphoid tissues is required for the generation and maintenance of immune responses against pathogens and is crucially controlled by the L-selectin (CD62L) leukocyte homing receptor. CD62L has adhesion and signaling functions and initiates the capture and ro...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Vassena, Lia, Giuliani, Erica, Koppensteiner, Herwig, Bolduan, Sebastian, Schindler, Michael, Doria, Margherita
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442509/
https://ncbi.nlm.nih.gov/pubmed/25822027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00611-15
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