ARID1B is a specific vulnerability in ARID1A-mutant cancers

Recent studies have revealed that ARID1A is frequently mutated across a wide variety of human cancers and also has bona fide tumor suppressor properties. Consequently, identification of vulnerabilities conferred by ARID1A mutation would have major relevance for human cancer. Here, using a broad scre...

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Bibliographische Detailangaben
Hauptverfasser: Helming, Katherine C., Wang, Xiaofeng, Wilson, Boris G., Vazquez, Francisca, Haswell, Jeffrey R., Manchester, Haley E., Kim, Youngha, Kryukov, Gregory V., Ghandi, Mahmoud, Aguirre, Andrew J., Jagani, Zainab, Wang, Zhong, Garraway, Levi A., Hahn, William C., Roberts, Charles W. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954704/
https://ncbi.nlm.nih.gov/pubmed/24562383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3480
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