ARID1B is a specific vulnerability in ARID1A-mutant cancers

Recent studies have revealed that ARID1A is frequently mutated across a wide variety of human cancers and also has bona fide tumor suppressor properties. Consequently, identification of vulnerabilities conferred by ARID1A mutation would have major relevance for human cancer. Here, using a broad scre...

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Bibliographic Details
Main Authors: Helming, Katherine C., Wang, Xiaofeng, Wilson, Boris G., Vazquez, Francisca, Haswell, Jeffrey R., Manchester, Haley E., Kim, Youngha, Kryukov, Gregory V., Ghandi, Mahmoud, Aguirre, Andrew J., Jagani, Zainab, Wang, Zhong, Garraway, Levi A., Hahn, William C., Roberts, Charles W. M.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954704/
https://ncbi.nlm.nih.gov/pubmed/24562383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3480
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