Early Airway Structural Changes in Cystic Fibrosis Pigs as a Determinant of Particle Distribution and Deposition

The pathogenesis of cystic fibrosis (CF) airway disease is not well understood. A porcine CF model was recently generated, and these animals develop lung disease similar to humans with CF. At birth, before infection and inflammation, CF pigs have airways that are irregularly shaped and have a reduce...

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Auteurs principaux: Awadalla, Maged, Miyawaki, Shinjiro, Alaiwa, Mahmoud H. Abou, Adam, Ryan J., Bouzek, Drake C., Michalski, Andrew S., Fuld, Matthew K., Reynolds, Karen J., Hoffman, Eric A., Lin, Ching-Long, Stoltz, David A.
Format: Artigo
Langue:Inglês
Publié: 2013
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3954455/
https://ncbi.nlm.nih.gov/pubmed/24310865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-013-0955-7
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