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Lentiviral-mediated phenotypic correction of cystic fibrosis pigs

Cystic Fibrosis (CF) is an autosomal recessive disease caused by mutations in CF transmembrane conductance regulator (CFTR), resulting in defective anion transport. Regardless of the disease-causing mutation, gene therapy is a strategy to restore anion transport to airway epithelia. Indeed, viral ve...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:JCI Insight
Prif Awduron: Cooney, Ashley L., Abou Alaiwa, Mahmoud H., Shah, Viral S., Bouzek, Drake C., Stroik, Mallory R., Powers, Linda S., Gansemer, Nick D., Meyerholz, David K., Welsh, Michael J., Stoltz, David A., Sinn, Patrick L., McCray, Paul B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027966/
https://ncbi.nlm.nih.gov/pubmed/27656681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88730
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