Lentiviral-mediated phenotypic correction of cystic fibrosis pigs

Cystic Fibrosis (CF) is an autosomal recessive disease caused by mutations in CF transmembrane conductance regulator (CFTR), resulting in defective anion transport. Regardless of the disease-causing mutation, gene therapy is a strategy to restore anion transport to airway epithelia. Indeed, viral ve...

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Cooney, Ashley L., Abou Alaiwa, Mahmoud H., Shah, Viral S., Bouzek, Drake C., Stroik, Mallory R., Powers, Linda S., Gansemer, Nick D., Meyerholz, David K., Welsh, Michael J., Stoltz, David A., Sinn, Patrick L., McCray, Paul B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027966/
https://ncbi.nlm.nih.gov/pubmed/27656681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88730
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