Lentiviral-mediated phenotypic correction of cystic fibrosis pigs

Cystic Fibrosis (CF) is an autosomal recessive disease caused by mutations in CF transmembrane conductance regulator (CFTR), resulting in defective anion transport. Regardless of the disease-causing mutation, gene therapy is a strategy to restore anion transport to airway epithelia. Indeed, viral ve...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Cooney, Ashley L., Abou Alaiwa, Mahmoud H., Shah, Viral S., Bouzek, Drake C., Stroik, Mallory R., Powers, Linda S., Gansemer, Nick D., Meyerholz, David K., Welsh, Michael J., Stoltz, David A., Sinn, Patrick L., McCray, Paul B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027966/
https://ncbi.nlm.nih.gov/pubmed/27656681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88730
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