Proteasome-dependent Degradation of Transcription Factor Activating Enhancer-binding Protein 4 (TFAP4) Controls Mitotic Division

TFAP4, a basic helix-loop-helix transcription factor that regulates the expression of a multitude of genes involved in the regulation of cellular proliferation, stemness, and epithelial-mesenchymal transition, is up-regulated in colorectal cancer and a number of other human malignancies. We have fou...

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Detalhes bibliográficos
Main Authors: D'Annibale, Sara, Kim, Jihoon, Magliozzi, Roberto, Low, Teck Yew, Mohammed, Shabaz, Heck, Albert J. R., Guardavaccaro, Daniele
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Protein Synthesis and Degradation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953283/
https://ncbi.nlm.nih.gov/pubmed/24500709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.549535
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