The CXCR1/2 ligand NAP-2 promotes directed intravascular leukocyte migration through platelet thrombi

Thrombosis promotes leukocyte infiltration into inflamed tissues, leading to organ injury in a broad range of diseases; however, the mechanisms by which thrombi guide leukocytes to sites of vascular injury remain ill-defined. Using mouse models of endothelial injury (traumatic or ischemia reperfusio...

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Main Authors: Ghasemzadeh, Mehran, Kaplan, Zane S., Alwis, Imala, Schoenwaelder, Simone M., Ashworth, Katrina J., Westein, Erik, Hosseini, Ehteramolsadat, Salem, Hatem H., Slattery, Robyn, McColl, Shaun R., Hickey, Michael J., Ruggeri, Zaverio M., Yuan, Yuping, Jackson, Shaun P.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2013
Assuntos:
Platelets and Thrombopoiesis
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3953078/
https://ncbi.nlm.nih.gov/pubmed/23550035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-09-459636
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