Occlusive thrombi arise in mammals but not birds in response to arterial injury: evolutionary insight into human cardiovascular disease

Mammalian platelets are small, anuclear circulating cells that form tightly adherent, shear-resistant thrombi to prevent blood loss after vessel injury. Platelet thrombi that form in coronary and carotid arteries also underlie common vascular diseases such as myocardial infarction and stroke and are...

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Detalhes bibliográficos
Main Authors: Schmaier, Alec A., Stalker, Timothy J., Runge, Jeffrey J., Lee, Dooyoung, Nagaswami, Chandrasekaran, Mericko, Patricia, Chen, Mei, Cliché, Simon, Gariépy, Claude, Brass, Lawrence F., Hammer, Daniel A., Weisel, John W., Rosenthal, Karen, Kahn, Mark L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Platelets and Thrombopoiesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186337/
https://ncbi.nlm.nih.gov/pubmed/21816834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-02-338244
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