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Damnacanthal, an effective inhibitor of LIM-kinase, inhibits cell migration and invasion
LIM-kinases (LIMKs) play crucial roles in various cell activities, including migration, division, and morphogenesis, by phosphorylating and inactivating cofilin. Using a bimolecular fluorescence complementation assay to detect the actin–cofilin interaction, we screened LIMK1 inhibitors and identifie...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The American Society for Cell Biology
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3952852/ https://ncbi.nlm.nih.gov/pubmed/24478456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E13-09-0540 |
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