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Ca(2+)/Calmodulin-dependent Protein Kinase IV-mediated LIM Kinase Activation Is Critical for Calcium Signal-induced Neurite Outgrowth

Actin cytoskeletal remodeling is essential for neurite outgrowth. LIM kinase 1 (LIMK1) regulates actin cytoskeletal remodeling by phosphorylating and inactivating cofilin, an actin filament-disassembling factor. In this study, we investigated the role of LIMK1 in calcium signal-induced neurite outgr...

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Detalhes bibliográficos
Main Authors: Takemura, Miyohiko, Mishima, Toshiaki, Wang, Yan, Kasahara, Jiro, Fukunaga, Kohji, Ohashi, Kazumasa, Mizuno, Kensaku
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2781398/
https://ncbi.nlm.nih.gov/pubmed/19696021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.006296
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