Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood-tumor and blood-brain barriers improves outcomes in a rat glioma model

[Image: see text] The blood-brain-barrier (BBB) prevents the transport of most anticancer agents to the central nervous system and restricts delivery to infiltrating brain tumors. The heterogeneous vascular permeability in tumor vessels, along with several other factors, creates additional barriers...

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Hauptverfasser: Aryal, Muna, Vykhodtseva, Natalia, Zhang, Yong-Zhi, Park, Juyoung, McDannold, Nathan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952428/
https://ncbi.nlm.nih.gov/pubmed/23603615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.04.007
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