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Multiple treatments with liposomal doxorubicin and ultrasound-induced disruption of blood-tumor and blood-brain barriers improves outcomes in a rat glioma model

[Image: see text] The blood-brain-barrier (BBB) prevents the transport of most anticancer agents to the central nervous system and restricts delivery to infiltrating brain tumors. The heterogeneous vascular permeability in tumor vessels, along with several other factors, creates additional barriers...

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Detalhes bibliográficos
Main Authors: Aryal, Muna, Vykhodtseva, Natalia, Zhang, Yong-Zhi, Park, Juyoung, McDannold, Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952428/
https://ncbi.nlm.nih.gov/pubmed/23603615
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2013.04.007
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