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Enhancement in blood-tumor barrier permeability and delivery of liposomal doxorubicin using focused ultrasound and microbubbles: evaluation during tumor progression in a rat glioma model

Effective drug delivery to brain tumors is often challenging because of the heterogeneous permeability of the “blood tumor barrier” (BTB) along with other factors such as increased interstitial pressure and drug efflux pumps. Focused ultrasound (FUS) combined with microbubbles can enhance the permea...

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Detalhes bibliográficos
Publicado no:Phys Med Biol
Main Authors: Aryal, Muna, Park, Juyoung, Vykhodtseva, Natalia, Zhang, Yong-Zhi, McDannold, Nathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365471/
https://ncbi.nlm.nih.gov/pubmed/25746014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1088/0031-9155/60/6/2511
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