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The Role of LAT-PLCγ1 Interaction in γδ T cell Development and Homeostasis
Linker for Activation of T cells, LAT, is a transmembrane adaptor protein vital for integrating TCR-mediated signals to modulate T cell development, activation, and proliferation. Upon T cell activation, LAT is phosphorylated and associates with Grb2, Gads, and PLCγ1 through its four distal tyrosine...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951746/ https://ncbi.nlm.nih.gov/pubmed/24523509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302493 |
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