Lataa...
The role of the LAT-PLC-γ1 interaction in T regulatory cell function
The interaction between the linker for activation of T cells (LAT) with phospholipase C (PLC-γ1) is important for T cell receptor (TCR)-mediated Ca(2+) signaling and MAPK activation. Knock-in mice harboring a mutation at the PLC-γ1 binding site (Y136) of LAT develop a severe lymphoproliferative synd...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2010
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3646363/ https://ncbi.nlm.nih.gov/pubmed/20130215 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902876 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|