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Role of LAT in the Granule-Mediated Cytotoxicity of CD8 T Cells

Linker for activation of T cells (LAT) is a transmembrane adaptor protein that is essential to bridge T cell receptor (TCR) engagement to downstream signaling events. The indispensable role of LAT in thymocyte development and T cell activation has been well characterized; however, the function of LA...

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Main Authors: Ou-Yang, Chih-wen, Zhu, Minghua, Fuller, Deirdre M., Sullivan, Sarah A., Chuck, Mariana I., Ogden, Sarah, Li, Qi-Jing, Zhang, Weiguo
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3416195/
https://ncbi.nlm.nih.gov/pubmed/22566687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00356-12
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