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Cytosolic PINK1 escapes from mitochondria to promote dendritic outgrowth

Dagda et al. showed in this issue that cytosolic PINK1 released from the mitochondrion promotes dendritic outgrowth. This neurite-promoting activity of PINK1 is associated with the kinase activities of protein kinase A and is impaired by a pathogenic mutation in PINK1. The study by Dagda et al. has...

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Detalhes bibliográficos
Main Authors: Tieu, Kim, Xia, Xu-Gang
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3951605/
https://ncbi.nlm.nih.gov/pubmed/24261349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jnc.12529
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