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Silencing of the Pink1 Gene Expression by Conditional RNAi Does Not Induce Dopaminergic Neuron Death in Mice

Transgenic RNAi, an alternative to the gene knockout approach, can induce hypomorphic phenotypes that resemble those of the gene knockout in mice. Conditional transgenic RNAi is an attractive choice of method for reverse genetics in vivo because it can achieve temporal and spatial silencing of targe...

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Bibliografiset tiedot
Päätekijät: Zhou, Hongxia, Falkenburger, Björn H, Schulz, Jörg B, Tieu, Kim, Xu, Zuoshang, Xia, Xu Gang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Ivyspring International Publisher 2007
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1820878/
https://ncbi.nlm.nih.gov/pubmed/17389931
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