Učitavanje...
Mdm2 is required for maintenance of the nephrogenic niche
The balance between nephron progenitor cell (NPC) renewal, survival and differentiation ultimately determines nephron endowment and thus susceptibility to chronic kidney disease and hypertension. Embryos lacking the p53-E3 ubiquitin ligase, Murine double minute 2 (Mdm2), die secondary to p53-mediate...
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| Glavni autori: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2014
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3951515/ https://ncbi.nlm.nih.gov/pubmed/24440154 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2014.01.009 |
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